1 DNA, GENES, AND THE CODE

DNA structure

Nature of genes

Homology

The genetic code

Translation

Transcription

Homologous recombination

2 MUTAGENESIS IN VIVO

Inherent mutation frequency

Spontaneous mutations

Repair of all mutation types

Mutators and Anti-mutators

Chemical Mutagenesis

Systems for the analysis of mutations

Effects of mutations

Numerology

Mutant detection

3 REGULATION

Themes in regulation

Regulation at the level of DNA

Regulation at the level of RNA

Regulation at the level of translation

Regulation at the level of protein

Fusions

Arrays

4 GENETIC ENGINEERING

Enzymes

Vector types

PCR

Generation of mutations in vitro

In vivo analysis

5 DELETIONS

Mechanism of formation

Screens/ selections for deletions

6 DUPLICATIONS AND INVERSIONS

Tandem duplications

Non-tandem duplications

Amplifications

Inversions

7 MOBILE GENETIC ELEMENTS

General classes of elements

Distribution and evolution of ISs

Effects of IS/Tn

Uses of Tns

8 SELECTIONS, SCREENS AND ENRICHMENTS

Selections

Screens

Enrichments

9 PLASMIDS AND CHROMOSOMES

Types of replicons

Replication functions

Partitioning

Conjugation

10 TRANSFORMATION

Natural transformation

Induced transformation

11 PHAGE

Molecular biology of phage

Uses of phage

12 COMPLEMENTATION

The normal case

Interspecific complementation

13 GENETIC MAPPING

Objective

Two-factor crosses

Deletion mapping

14 SUPPRESSION

Introduction

Informational suppressors

Non-informational suppressors

15 EVOLUTION

16 SCIENCE AND SOCIETY

INDEX 

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